The Kinase Research Portal has compiled what they consider the 100 best/most popular articles of the last year. The list (via the linked header for this post) is could be used as means of taking the pulse of kinase research.
Takeaways:
-gene target interest is very broad. I counted at least 25 different gene targets as article themes.
-well-understood targets draw the most attention: Bcr-Abl and EGFR papers were the theme of at least 12 of the 100 papers.
-the most popular article subject without a drug yet developed: PI-3 (6 articles)
-the most popular article: Dario Alessi's seminal LKB1 article.
-surprising attention: DAPK (though with only 3 articles, one shouldn't read too much into this.)
-notable for it's absence: RAF (only article #100), popular RTK targets VEGFR and PDGFR. Also, I think there was only one Aurora-themed article, and little attention to cell cycle kinases in general.
Showing posts with label cool. Show all posts
Showing posts with label cool. Show all posts
Wednesday, January 24, 2007
Way cool kinase target popularity charts
The Kinase Research Portal has a cool application (linked in the header to this post) that shows kinase publication history and allows you to see target-specific publication trend graphs. Here's an example showing p38 publication trends (with a surprisingly steep upward trajectory.)
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